Herbal Treatment of Major Depression: Scientific Basis and Practical Use
Scott D. Mendelson
This unique volume presents new understandings of the neurochemical
nature of major depression, and how herbs and their constituent
flavonoids and terpenes appear to address some of the mechanisms now
thought to be involved. It explores how recent studies of the rapid
antidepressant effects of ketamine inform neuroscientists about deep
intracellular mechanisms of antidepressant action that have little to do
with simple enhancement of monoaminergic activity. These mechanisms
include actions on PI3K, Akt, mTOR, GSK3, BDNF, and other intracellular
pathways. New theories of the pathophysiology underlying major
depression, such as oxidative damage, inflammation, stress and insulin
resistance are then explored.
nature of major depression, and how herbs and their constituent
flavonoids and terpenes appear to address some of the mechanisms now
thought to be involved. It explores how recent studies of the rapid
antidepressant effects of ketamine inform neuroscientists about deep
intracellular mechanisms of antidepressant action that have little to do
with simple enhancement of monoaminergic activity. These mechanisms
include actions on PI3K, Akt, mTOR, GSK3, BDNF, and other intracellular
pathways. New theories of the pathophysiology underlying major
depression, such as oxidative damage, inflammation, stress and insulin
resistance are then explored.
Категории:
Год:
2021
Издание:
1
Издательство:
CRC Press
Язык:
english
Страницы:
448
ISBN 10:
1032087153
ISBN 13:
9781032087153
Файл:
PDF, 5.22 MB
IPFS:
,
english, 2021
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